WebMultinucleated cells could be also induced by 12-O-tetradecanoylphorbol 13-acetate (TPA) in 5F9A cells. This effect was mediated by protein kinase C. Possible mechanisms of multinucleation by TPA were hypothesized to be either karyokinesis without cytokinesis or … WebMay 7, 2024 · Classically, the decision whether to divide further is made after cell division is completed by cytokinesis and can be triggered by intrinsic or extrinsic factors. …
Syncytium - Wikipedia
WebMorphological characteristics of mononucleated cells, binucleated cells, and multinucleated cells as well as necrotic and apoptotic cells and nuclear buds are also described. These criteria are illustrated by a series of schematic diagrams as well as a comprehensive set of colour photographs that are of practical assistance during the scoring ... WebMar 1, 2024 · This leads to conditions such as aneuploidy, where a cell has several extra or missing chromosomes; polyploidy, where cytokinesis does not occur and a cell has more than a diploid set of chromosomes; or multinucleated cells, where more than one nucleus is present in a cell. These can lead to genetic disordersor even cancers. ionosphere blue
Karyokinesis - an overview ScienceDirect Topics
WebDec 17, 2013 · Multinucleated Reed-Sternberg (RS) cells are pathognomonic for classical Hodgkin lymphoma (HL), and their presence is essential for diagnosis. How these giant tumor cells develop is controversial, however. It has been postulated that RS cells arise from mononucleated Hodgkin cells via endomitosis. WebJun 18, 2024 · In our study, menin depletion led to defects in spindle assembly and chromosome congression during early mitosis, lagging chromosomes during anaphase, defective cytokinesis, multinucleated interphase cells, and cell death. In addition, pharmacological inhibition of the menin-MLL1 interaction also led to similar cell division … WebBecause many cells fuse together, syncytia are also known as multinucleated cells, giant cells, or polykaryocytes. [11] During infection, viral fusion proteins used by the virus to enter the cell are transported to … on the crest of crossword