Human timp-2
WebThe concentration of CHI3L1 was measured by a human sandwich enzyme-linked immunosorbent assay (ELISA) (DC3L10, R&D Systems, Minneapolis, MN, USA) … WebNov 20, 2003 · Although TIMP-2 was originally characterized as a suppressor of tumor invasion due to its ability to bind and inhibit MMP-2, 11 and overexpression of TIMP-2 was previously shown to reduce invasion ...
Human timp-2
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WebMay 9, 2012 · Biotinylated anti-Human TIMP1: 2 vials: Recombinant Human TIMP1 Standard (lyophilized) 2 vials: Stop Solution: 1 x 8ml: TIMP1 Microplate (12 x 8 wells) 1 unit: ... Ab100606 MMP-2 ELISA Ab100610 MMP-9 ELISA Ab100652 TIMP-1 ELISA Ab100653 TIMP-2 ELISA Thank you in advance Kind regards. Read More. Abcam community … WebThe Quantikine Human TIMP-2 Immunoassay is a 4.5 hour solid phase ELISA designed to measure TIMP-2 levels in cell culture supernates, serum, plasma, and saliva. It contains …
WebMay 4, 2024 · Product Summary. The Quantikine Human TIMP-2 Immunoassay is a 4.5 hour solid phase ELISA designed to measure TIMP-2 levels in cell culture supernates, … WebSimply select your targets of interest to find the assay that meets your needs. MMPs have many different functions and actions in the body, whereas TIMPs work to inhibit the actions of MMPs. Studying MMPs and their inhibitors, TIMPs, together can reveal disruptions in the balance of these two proteins, providing insights into disease states.
WebTissue inhibitor of metalloproteinase-2 (TIMP2) is a 21 kDa protein mainly expressed in melanoma and renal tubular cells. TIMP2 inhibits matrix metalloproteinases by binding to … The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMP), a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing th…
WebHuman TIMP-2 inhibits the activity of activated mouse MMP-9 (100 ng/mL). The is IC 50 ≤ 34 ng/mL. Application Bioassay. Application Notes BioLegend carrier-free recombinant proteins provided in liquid format are shipped on blue-ice. Our comparison testing data indicates that when handled and stored as recommended, the liquid format has equal ...
WebThe RayBio ® Human TIMP-4 IQELISA™ Kit is a modified ELISA assay with high sensitivity qPCR readout for the quantitative measurement of Human TIMP-4 in serum, plasma, and cell culture supernatants. This assay employs an antibody specific for Human TIMP-4 coated on a 96-well PCR plate. Standards and samples are pipetted into the wells and ... how does ubuntu make moneyWebTissue Inhibitors of Metalloproteinases (TIMPs) comprise a family of four inhibitors known as TIMP-1, TIMP-2, TIMP-3, and TIMP-4. Each member of the TIMP family has its own … fender 74 jazz bassWeb일반 설명. Native MMP-9-Lipocalin-TIMP-1 complex from stimulated human neutrophils. The ternary MMP-9/lipocalin/TIMP-1 complex behaves like the Pro-MMP-9/TIMP-1 complex, acting as an inhibitor of active MMPs. Following activation, the complex acts as a gelatinase, with reduced activity. Native MMP-9-Lipocalin-TIMP-1 complex from stimulated ... how does urusei yatsura endWebTIMP-2 is a ~21 kDa (nonreduced) or a ~24 kDa (reduced) protein on SDS-PAGE that is expressed by a variety of cell types. It forms a non-covalent, stoichiometric complex with … how does saudi arabia make it rainWebThe present specification discloses a novel use of granulocyte colony-stimulating factor receptor or colony-stimulating factor 3 receptor (CSF3R) as a biomarker and as a therapeutic target for pulmonary fibrosis. The present specification discloses a treatment mechanism, a treatment method, and a treatment drug involving CSF3R for pulmonary … how does smoking cause permanent lung damageWebDec 27, 2024 · The Quantikine Human TIMP-2 Immunoassay is a 4.5 hour solid phase ELISA designed to measure TIMP-2 levels in cell culture supernates, serum, plasma, and saliva. It contains CHO cell-expressed recombinant human TIMP-2, and antibodies raised against the recombinant protein. Natural human TIMP-2 showed dose-response curves … fender 75 jazz bass pickupsWebTIMP-2 can also act through a matrix metalloproteinase (MMP)-independent mechanism inhibiting endothelial cell proliferation in vitro. TIMP-2 mediates anti-angiogenic activities in vivo. TIMP-2 is a target gene of the microRNA-miR-22. TIMP-2 functions as a biomarker for cell cycle arrest. fender 77 jazz bass