WebbFan Lai 1 , Ramin Shiekhattar 2 Affiliations 1 Wistar Institute, Philadelphia, PA 19104, USA. 2 Wistar Institute, Philadelphia, PA ... Electronic address: [email protected]. PMID: 24480293 PMCID: PMC4484728 DOI: 10.1016/j.gde.2013.11.017 Abstract In the past ... Webb1 juni 2024 · The authors thank the Shiekhattar laboratory members for discussions and helpful comments. RS is supported by the University of Miami Miller School of Medicine , …
PEOPLE – Shiekhattar Lab
Webb1 sep. 2024 · Activating mutations in the mitogen-activated protein kinase (MAPK) cascade, also known as the RAS-MEK-extracellular signal-related kinase (ERK1/2) pathway, are an underlying cause of >70% of human cancers. While great strides have been made toward elucidating the cytoplasmic components of MAPK signaling, the key downstream … fritz barthel armaturen gmbh \u0026 co k
The Integrator complex at the crossroad of coding and noncoding …
WebbDavid Baillat 1 , Ramin Shiekhattar. Affiliation 1 Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA. PMID: 19470757 PMCID: PMC2715800 DOI: 10.1128/MCB.00380-09 Abstract Argonaute (Ago) proteins through their ... Webb16 apr. 2024 · Ramin Shiekhattar, Ph.D. “One of the major strategies cancer cells use to avoid chemotherapy is to basically stop growing,” said Dr. Shiekhattar, co-leader of the Cancer Epigenetics Research Program and senior author on … Webb2 okt. 2014 · In unicellular organisms, initiation is the rate-limiting step in transcription; in metazoan organisms, the transition from initiation to productive elongation is also important. Here, we show that the RNA polymerase II (RNAPII)-associated multiprotein complex, Integrator, plays a critical role in b … fritz barthel