WebSmall-molecule modulators of the circadian clock: Pharmacological potentials in circadian-related diseases Drug Discovery Today 10.1016/j.drudis.2024.03.015 WebDec 1, 2024 · TLR4 biased small molecule modulators Pharmacology & Therapeutics, Volume 228, 2024, Article 107918 Show abstract Research article Pathophysiological and pharmacological relevance of TLR4 in peripheral immune cells after stroke Pharmacology & Therapeutics, Volume 228, 2024, Article 107933 Show abstract Research article
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WebToll-like receptor 4, a highly conserved protein of innate immunity, is responsible for the regulation and maintenance of homeostasis. It has been implicated in the progression of ulcerative colitis (UC) by interacting with its downstream pathway myeloid differentiation factor 88 (MyD88) and nuclear factor kappa B (NF-κB). This study aimed to evaluate the … WebOct 2, 2008 · Structure–Activity Relationship Analysis of Imidazoquinolines with Toll-like Receptors 7 and 8 Selectivity and Enhanced Cytokine Induction. Journal of Medicinal Chemistry 2014, 57 (2) , 339-347. DOI: 10.1021/jm4004957. Amanda Shanks Huynh, Woo Jin Chung, Hyun-Il Cho, Valerie E. Moberg, Esteban Celis, David L. Morse, and Josef Vagner . WebTLR4 biased small molecule modulators Article Jun 2024 Cong Lin Hongshuang Wang Miyuan Zhang [...] Xiaohui Wang Biased pharmacological modulators provide potential therapeutic benefits,... can you play slippi with an xbox controller